Cologuard

If you are 45 and older and at average risk for colon cancer, Cologuard is a noninvasive screening option that is available by prescription only and may be right for you.

On September 20th, 2019, FDA approved the expansion of the Cologuard label to include adults ages 45-49 at average risk for colorectal cancer. Cologuard is now approved to screen adults 45 years old and older at average risk for colorectal cancer, aligned with the 2018 American Cancer Society guidelines, which made a recommendation to start screening at age 45 to help detect and prevent colorectal cancer.

Have questions? Find helpful FAQs below or call us at 1-844-870-8870.

Can Cologuard be used for people ages 45-49?

Yes. Cologuard is now approved to screen adults 45 years old and older at average risk for colorectal cancer. This does not include individuals who have a personal or family history of CRC, have IBD, personal history of adenomas; have a relevant familial (hereditary) cancer syndrome or have had a previous positive CRC screening result in the past 6 months. Patients should talk to their healthcare provider to determine if Cologuard is appropriate for them. 

I thought CRC screening was supposed to start at age 50. Why is it changing?

In May 2018, the American Cancer Society revised its CRC screening guidelines to include patients 45 years or older at average risk of CRC. The ACS based this recommendation on increased CRC incidence and mortality rates in this population. 

How can I get Cologuard?

Cologuard is a noninvasive screening option that is available by prescription only. Call or make an appointment with your healthcare provider to request Cologuard.

Will my insurer cover the test?

Currently, ~74% of Cologuard patients 45-49 have had no out-of-pocket cost for screening.  

  • Many national and regional payers have begun paying for CRC screening at 45. Exact Sciences continues to work with payers to expand coverage and access for patients ages 45-49.

Visit the insurance page for more details by clicking here.

Exact Sciences estimate based on historical patient billing. Rate of coverage varies by state and region. Exceptions for coverage may apply, only your insurer can confirm how Cologuard would be covered for you.

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