How effective is cologuard?

In a clinical study of 10,000 people ages 50-84, Cologuard found*:

of colon cancers
of high-risk precancers

The Cologuard test result should be interpreted with caution. A positive test result does not confirm the presence of cancer. Patients with a positive test result should be referred for diagnostic colonoscopy. A negative test result does not confirm the absence of cancer. Patients with a negative test result should discuss with their doctor when they need to be tested again. False positives and false negative results can occur. In a clinical study, 13% of people without cancer received a positive result (false positive) and 8% of people with cancer received a negative result (false negative). Rx only.

*Imperiale TF, Ransohoff DF, Itzkowitz SH, et al. Multitarget stool DNA testing for colorectal-cancer screening. N Engl J Med. 2014;370(14):1287-97.

See Important Risk Information »

How it works

Cologuard uses a special kind of technology that’s quite innovative. It’s called sDNA (stool DNA) technology and it detects cancer and highest-risk precancers. It makes Cologuard the most accurate, noninvasive colon cancer screening test that you can rely on. Learn more »

Carousel with helpful links. Navigation buttons disabled for a screen reader user.