How effective is cologuard?

Among 10,000 people Cologuard found*:

of colon cancers
of high-risk precancers

Both false positives and false negatives do occur. In a clinical study of Cologuard, 13% of people without cancer or precancer tested positive (87% specificity). Any positive should be followed by a diagnostic colonoscopy. Following a negative result, patients should continue participating in a screening program at an interval and with a method appropriate for the individual patient. Cologuard performance when used for repeat testing has not been evaluated or established.

*Imperiale TF, Ransohoff DF, Itzkowitz SH, et al. Multitarget stool DNA testing for colorectal-cancer screening. N Engl J Med. 2014;370(14):1287-97.

See Important Risk Information »

How it works

Cologuard uses a special kind of technology that’s quite innovative. It’s called sDNA (stool DNA) technology and it detects cancer and highest-risk precancers. It makes Cologuard the most accurate, noninvasive colon cancer screening test that you can rely on. Learn more »

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