How effective is Cologuard?
In a 10,000-patient clinical study, Cologuard found 92% of colon cancers.1 It also found 69% of high-risk precancers (high-grade dysplasia), those most likely to develop into cancer.
Both false positives and false negatives do occur. In a clinical study of Cologuard, 13% of people without cancer or precancer tested positive. Any positive should be followed by a diagnostic colonoscopy. Following a negative result, patients should continue participating in a screening program at an interval and with a method appropriate for the individual patient. Cologuard performance when used for repeat testing has not been evaluated or established.